New research by Cyprotex in the field of metformin drug-drug interactions has been published in Pharmacology Research & Perspectives. The publication assists in further understanding the mechanism behind clinically observed DDIs with the common co-medication, metformin.

Read our blog and download the publication.

Cyprotex offers a full range of in vitro ADME, DDI and toxicology services including both screening and regulatory support:


  • Drug metabolism
  • Permeability and transporters
  • DDI studies
  • Distribution and protein binding
  • Solubility and physicochemical properties
  • In silico predictions


  • High content screening
  • Microelectrode array
  • 2D and 3D cell-based models
  • Organ specific toxicity
    • Hepatotoxicity
    • Cardiotoxicity
    • Neurotoxicity
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  • Genotoxicity
  • Mechanistic toxicology